Haemophilia B is caused by Variants (mutations) in the F9 gene which codes for coagulation factor IX. There are currently 1095 unique variants in the F9 gene compiled within this database corresponding to 3713 individual cases.
If you find this website useful, please reference our publication:
Rallapalli, P.M., Kemball-Cook, G., Tuddenham, E.G., Gomez, K., & Perkins, S.J. 2013. An interactive mutation database for human coagulation factor IX provides novel insights into the phenotypes and genetics of haemophilia B. J.Thromb.Haemost. available from: PM:23617593
What can you do in this database?
You can search for all the mutations reported in the F9 gene prior to the database release date. You can look in the database for all the sequence, structural and statistical information for the mutations. You can also submit new mutations and contribute to the genetic services provided through this database.