Novel Missense Variant Prediction

  • The Effects of any theoretical missense mutations can be predicted here.
  • Codons are numbered with respect to the HGVS nomenclature-with codon 1 representing the first residue (Met) of the signal peptide.
  • You need to select any one option for the "Variant Amino Acid". If nothing is chosen no result would be shown.

FIX Multiple Sequence Alignment in primates    

Note: Clicking and Dragging the mouse over the sequences will take you across the sequence limits
Note: All numbering is for human FIX and is HGVS